Hydroformylation of formaldehyde to glycolaldehyde:An alternative synthetic route for ethylene glycol

• 作者: Jie Wei Maoshuai Li Meiyan Wang Shixiang Feng Weikang Dai Qi Yang Yi Feng Wanxin Yang Cheng Yang Xinbin Ma
• 来源期刊: 中国化学工程学报（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Review
• 页码范围: 3-16
• 页数: 14页
• 语种: 英文

摘要

Hydroformylation of formaldehyde to glycolaldehyde (GA),as a vital reaction in both direct and indirect process of syngas to ethylene glycol (EG),shows great advantages in the aspects of the process complex-ity and clean production.The hydroformylation of formaldehyde to GA is thermodynamically unfavour-able,requiring the development of highly efficient hydroformylation catalytic systems,appropriate reaction conditions and in-depth understanding of the reaction mechanisms.In this review,we have made a detailed summary on the reaction in terms of the reaction network,thermodynamics,metal com-plex catalysts (including central metals and ligands),reaction conditions (e.g.,temperature,pressure,formaldehyde source and solvent) and promoters.Furthermore,the reaction mechanisms,involving neu-tral and anionic complex in the catalytic cycle,have been summarized and followed by a discussion on the impact of the crucial intermediates on the reaction pathways and product distribution.A brief over-view of product separation and catalyst recovery has been presented in the final part.This review gives new insights into the factors that impact on the formaldehyde hydroformylation and reaction mecha-nisms,which helps to design more efficient catalytic systems and reaction processes for EG production via the hydroformylation route.