Lewis Acid Enables Ketone Phosphorylation:Synthesis of Alkenyl Phosphonates

• 作者: Xiao-Hong Wei Chun-Yuan Bai Lian-Biao Zhao Ping Zhang Zhen-Hua Li Yan-Bin Wang Qiong Su
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Concise Reports
• 页码范围: 1855-1860
• 页数: 6页
• 语种: 英文
• DOI: 10.1002/cjoc.202100083

摘要

Main observation and conclusion An efficient Lewis acid enabled ketones phosphonylation to synthesize vinylphosphonates has been developed.This method relays on ketone hydrophosphonylation/α-hydroxy phosphonates unimolecular elimination (E1) dehydration cascade reaction sequence.Vari-ous C—P bond formation products were obtained in moderate to excellent yields with water as the only byproduct in the reaction.