Hashimoto's Thyroiditis is a common Autoimmune disease, and clinical related research has made great progress. This article summarizes the clinical and experimental studies on Hashimoto's Thyroiditis in recent years, summarizes in five aspects from its western medicine pathogenesis(Genetics, Environment, Gender, Immunity, mi RNA), traditional Chinese medicine etiology and pathogenesis, western medicine treatment(Glucocorticoid therapy, Chemokine receptor antagonist therapy, Nutrition therapy), traditional Chinese medicine therapy(Treatment by type, Treatment by stages, Treatment by liver, Treatment by spleen and kidney, Treatment by gas, blood, phlegm and blood stasis, Prescription of experience, Characteristic theory of physician and Characteristic therapy of Traditional Chinese Medicine)and combine traditional Chinese and western medicine treatment, and puts forward the integrated treatment of traditional Chinese and western medicine is the general trend of future diagnosis and treatment of Hashimoto thyroiditis.