Rhodium(Ⅰ)-Catalyzed Enantioselective C(sp3)—H Functionaliza-tion via Carbene-Induced Asymmetric Intermolecular C—H Insertion

• 作者: Bo Liu Ming-Hua Xu
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Concise Reports
• 页码范围: 1911-1915
• 页数: 5页
• 语种: 英文
• DOI: 10.1002/cjoc.202100040

摘要

Main observation and conclusion Transition-metal-catalyzed C—H insertion of metal-carbene represents an excellent and powerful approach for C—H functionaliza-tion.However,despite remarkable advances in metal-carbene chemistry,transition metal catalysts that are capable of enantioselec-tive intermolecular carbene C—H insertion are mainly constrained to dirhodium(Ⅱ) and iridium(Ⅲ)-based complexes.Herein,we dis-close a new version of asymmetric carbene C—H insertion reaction with rhodium(Ⅰ) catalyst.