Toxic effects of nano-TiO2 in bivalves—A synthesis of meta-analysis and bibliometric analysis

• 作者: Zhuoqing Li Menghong Hu Hanting Song Daohui Lin Youji Wang
• 来源期刊: 环境科学学报（英文版）
• 年，卷（期）: 2021,（6）
• 页码范围: 188-203
• 页数: 16页
• 语种: 英文

摘要

Since the beginning of the 21st century,the increasing production and application of nano-TiO2 in consumer products have inevitably led to its release into aquatic systems and there-fore caused the exposure of aquatic organisms,resulting in growing environmental con-cerns.However,the safety of nano-TiO2 in aquatic environments has not been system-atically assessed,especially in coastal and estuary waters where a large number of filter-feeding animals live.Bivalves are considered around the world to be a unique target group for nanoparticle toxicity,and numerous studies have been conducted to test the toxic effects of nano-TiO2 on bivalves.The aim of this review was to systematically summarize and ana-lyze published data concerning the toxicological effects of nano-TiO2 in bivalves.In partic-ular,the toxicity of nano-TiO2 to the antioxidant system and cell physiology was subjected to meta-analysis to reveal the mechanism of the toxicological effects of nano-TiO2 and the factors affecting its toxicological effects.To reveal the cooperation,hot keywords and co-citations in this field,bibliometric analysis was conducted,and the results showed that the toxicological molecular mechanisms of nano-TiO2 and the combined effects of nano-TiO2 and other environmental factors are two major hot spots.Finally,some perspectives and in-sights were provided in this review for future research on nano-TiO2 toxicology in bivalves.