Design,Synthesis and Biological Evaluation of Novelα-Acyloxycarboxamide-Based Derivatives as c-Met Inhibitors

• 作者: Yu-juan Feng Yu-Lin Ren Li-Ming Zhao Guo-Qiang Xue Wen-Hao Yu Jia-Qi Yang Jun-Wei Liu
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: Comprehensive Reports
• 页码范围: 2241-2250
• 页数: 10页
• 语种: 英文
• DOI: 10.1002/cjoc.202100106

摘要

Dysregulated HGF/c-Met signalling has been associated with many human cancers,poor clinical outcomes,and even resistance acqui-sition to some approved targeted therapies.