Genomic evidence of lung carcinogenesis associated with coal smoke in Xuanwei area,China

• 作者: Honglei Zhang Chao Liu Li Li Xu Feng Qing Wang Jihua Li Shaobin Xu Shuting Wang Qianlu Yang Zhenghai Shen Jinhua Su Xiaosan Su Ruifen Sun Xuhong Zhou Junliang Wang Yongchun Zhou Baowei Jiao Wanbao Ding Xianbao Cao Yue Wang Yunchao Huang Lianhua Ye
• 来源期刊: 国家科学评论（英文版）
• 年，卷（期）: 2021,（12）
• 所属期刊栏目: BRIEF COMMUNICATION
• 页码范围: 10-14
• 页数: 5页
• 语种: 英文

摘要

Xuanwei area,in southwestern China,harbors the highest female lung cancer rate in the country (Supplementary Table 1) [1].Epidemiological studies have shown that lung cancer incidence in Xuanwei area is associated with the use of different types of local coal for household cooking and heating [2].The genomic landscape of Xuanwei female adenocar-cinoma (XWFA),the most distinctive feature of lung cancer in Xuanwei,has yet to be elucidated systematically.Here,we provide the fundamental resource of genomic datasets for further exploration of XWFA molecular mechanisms and development oftargetable therapy.