Research progress on methylation of osteosarcoma-related genes

• 作者: Tai-Yong Wu Jian Li Hai-Jun Fu Cai-Tong Cheng Zhi Lv Yi Feng
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2021,（24）
• 所属期刊栏目: Review and lectures
• 页码范围: 61-65
• 页数: 5页
• 语种: 英文

摘要

The occurrence of osteosarcoma is related to a variety of oncogenes and tumor suppressor genes. DNA methylation is an important feature of epigenetics, which can cause the activation of oncogenes and the inactivation of tumor suppressor genes. DNA methylation is an important factor in the study of metastasis, recurrence and drug resistance of osteosarcoma. To study the methylation of osteosarcoma-related genes provides theoretical support for the study of the occurrence, metastasis and drug resistance of osteosarcoma, and provides a theoretical basis for clinical diagnosis, prognosis prediction, targeted therapy and the study of new drugs.