Audiovisual production, as social media, plays a considerable role in cultural exchanges around the world, for it is one of the ways for people to know more about exotic cultures. At the same time, due to language barriers, the importance of subtitle trans?lation is gradually recognized. The subtitle translation can go beyond the limits of time and space to faithfully reproduce the story plot and skillfully convey the feelings. From the perspective of relevance theory, the subtitle translation of The Big Bang Theory is chosen as a case in this paper to analyze the inferential process in the following three relevant aspects:relevance in context, rele?vance in culture, and relevance in the audience.