Isotope geochronology and isotope geochemistry are im-portant branches of geochemistry. They are based on variations in radiogenic or stable isotope ratios of elements and provide key chemical fingerprints to understand dynamic evolution of the Earth and other planetary bodies from the past to the pres-ent, and from their interior to exterior systems. Benefiting from the progresses in modern analytical instrumentations and tech-niques in the past two decades, isotope geochronology and iso-tope geochemistry have been booming and achieved great ad-vances, from theoretical calculation, analytical capability, fun-damental principles to diverse applications. They have also been extended to very broad and new fields.