Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

• 作者: Hongpu Wei Jinjie Cui Kaili Lin Jing Xie Xudong Wang
• 来源期刊: 骨研究（英文版）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: REVIEWS
• 页码范围: 46-64
• 页数: 19页
• 语种: 英文

摘要

INTRODUCTION Tumors, severe infection, osteoporosis, osteonecrosis, and some congenital malformations can cause large bone defects, which remain challenging in clinical practice.1 Bone defects induced by various causes are currently one of the principal causes of morbidity and disability, which decrease quality of life and endanger lives.