Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors

• 作者: Shenghua Gao Tianguang Huang Letian Song Shujing Xu Ysen Cheng Srinivasulu Cherukupalli Dongwei Kang Tong Zhao Lin Sun Jian Zhang Peng Zhan Xinyong Liu
• 来源期刊: 药学学报（英文版）
• 年，卷（期）: 2022,（2）
• 所属期刊栏目: Reviews
• 页码范围: 581-599
• 页数: 19页
• 语种: 英文

摘要

Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection.Herein,we briefly provide a concise report on the medicinal chemistry strategies towards the develop-ment of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective.