Identification of CHMP4C as a new risk gene for inherited dilated cardiomyopathy

• 作者: Nianwei Zhou Lu Tang Yingying Jiang Xuejie Li Shifang Shan Bo Yuan Shengmei Qin Cuizhen Pan Xiaolin Wang Xianhong Shu Zilong Qiu Junbo Ge
• 来源期刊: 遗传学报
• 年，卷（期）: 2022,（2）
• 所属期刊栏目: Letter to the Editor
• 页码范围: 169-172
• 页数: 4页
• 语种: 英文

摘要

Dilated cardiomyopathy(DCM)is a primary myocardial disease of unknown cause that is characterized by ventricular enlargement and ventricular systolic dysfunction(Reichart et al.,2019).DCM exhibits obvious heterogeneity,and its outcomes extend from arrhythmia to heart failure.Early arrhythmia is a common condition that may pro-gressively become aggravated,and death can occur at any stage of the disease.The most serious complications are heart failure and sudden death(McNally et al.,2013).