Molecular testing for acute myeloid leukemia

• 作者: Dahui Qin
• 来源期刊: 癌症生物学与医学（英文版）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: REVIEW
• 页码范围: 4-13
• 页数: 10页
• 语种: 英文
• DOI: 10.20892/j.issn.2095-3941.2020.0734

摘要

In the era of personalized medicine, information on molecular change at the gene level is important for patient care. Such information has been used for disease classification, diagnosis, prognosis, risk stratification, and treatment, which is especially important in cancer patient care. Many molecular tests exist and can be used to detect the molecular changes at gene level. These tests include, but are not limited to, karyotyping, endpoint polymerase chain reaction (PCR), real-time PCR, Sanger sequencing, pyrosequencing, next-generation sequencing, and so forth. How to use the right tests for the right patients at the right time is essential for optimal patient outcome. This review puts together some information on molecular testing for acute myeloid leukemia.