The adsorption removal of anti-inflammatory drugs from water by diverse materials has drawn great attention.This study investigated the adsorption of sulfamethoxazole (SMX) by two types of materials,UiO-66 and UiO-66-BC composites.Highly porous MOF composites with functional groups were synthe-sized by combining UiO-66 with corncob-based biochar at different molar ratios.SEM results showed that macroporosity of UiO-66-BC composites was increased by increasing the ratio of biochar.It was found that UiO-66-BC composites displayed highly improved adsorption performance of SMX relative to pristine UiO-66.UiO-66-BC (5%) had the highest SMX adsorption capacity,about 2.4 times those of pristine UiO-66.It was the high surface area of UiO-66 and redundant functional groups of biochar that increased the adsorption performance of composites.Moreover,UiO-66-BC can be reused and displayed the competitive adsorption efficiency after successive adsorption,which made it a potential adsorbent for the removal of SMX from water.