Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility

• 作者: Jia-Jun Qiu Ting-Ting Yang Yi-Fan Li Wen-Hao Qian Xuan-Yong Liu
• 来源期刊: 稀有金属（英文版）
• 年，卷（期）: 2022,（2）
• 所属期刊栏目: SPECIAL TOPIC:ANTIBACTERIAL MATERIALS
• 页码范围: 630-638
• 页数: 9页
• 语种: 英文

摘要

Although titanium and its alloys are extensively used in orthopedics and dentistry fields,implant failures still happen because of implant-associated infections.Herein,Au@Ag@Pt core-shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface and the antibacterial activity and bio-compatibility were investigated.The results showed that antibacterial rates of Ti-Au@Ag@Pt against S.epider-midis and P.aeruginosa were 89.7％ and 92.7％,respec-tively.Besides,Ti-Au@Ag@Pt showed no obvious cell toxicity with MC3T3-E1 cells grew well on the sample surface.It was discovered that the Pt shell layer on Ti-Au@Ag@Pt slowed down the Ag ion release rate which endowed medical titanium surface with both antibacterial activity and good biocompatibility.