Silver nanoparticles(AgNPs)are widely adopted in polyurethane foams(PUFs)as a type of antibac-terial agent.However,due to its poor interfacial interaction,AgNPs are difficult to be dispersed in the polymer matrix uniformly,which deteriorates the enhancement effect.In this paper,silver-coated graphene nanocomposite(Ag/GO)is prepared by an enzyme reductant which is efficient and non-toxic.Compared with traditional antibacterial agent,the Ag/GO nanoparticles can be uniformly dispersed in the nanocomposite,which means that Ag/GO can be well-dispersed into the polyurethane foams(PUFs).Compared with AgNPs modified PUFs,the as-prepared Ag/GO modi-fied PUFs have a 1.85%improvement in resilience,7.9%improvement in tensile strength,6.52%improvement in tensile elongation,and 8.74%improvement in bacteriostats rate at a loading of 0.4%.