Highly sensitive luminescent lanthanide metal-organic framework sensor for L-kynurenine

• 作者: Ting Tang Min Liu Zhao Chen Xingxiang Wang Chunguang Lai Liwen Ding Chenghui Zeng
• 来源期刊: 稀土学报（英文版）
• 年，卷（期）: 2022,（3）
• 所属期刊栏目: SPECTROSCOPY, LUMINESCENCE AND PHOSPHORS
• 页码范围: 415-420
• 页数: 6页
• 语种: 英文

摘要

L-kynurenine (L-kyn) is a marker of prostate cancer.At present,the expensive instruments are usually applied to detect L-kyn clinically,which limits its wide application for cancer diagnosis.Herein,three lanthanide metal-organic frameworks ([Ln(CHO2)3]n,Ln Eu,Gd,and Tb) were designed and obtained,and detailly characterized by single crystal X-ray diffraction (SCXRD),powder X-ray diffraction(PXRD),Fourier transform infrared spectroscopy (FT-IR),thermogravimetric analysis (TGA),and lumi-nescence spectroscopy.Further study reveals that[Tb(CHO2)3]n is a highly selective,ultra-sensitive,of strong anti-interference,highly stable,and non-expensive sensor for prostate cancer marker L-kyn.The limit of detection (LOD) for L-kyn sensing is a highly sensitive value of 1.0 × 10-9 mol/L.Furthermore,the sensing mechanism is discussed in detail.