Direct C(sp3)-H Sulfonylation of Xanthene Derivatives with Sodium Sulfinates by Oxidative Copper Catalysis

• 作者: Qinghao Song He Zhao Yanping Sun Huanfeng Jiang Min Zhang
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2022,（3）
• 所属期刊栏目: Concise Reports
• 页码范围: 371-377
• 页数: 7页
• 语种: 英文
• DOI: 10.1002/cjoc.202100767

摘要

By employing a readily available CuCl/DDQ catalyst system,we herein report a direct C(sp3)-H sulfonylation of xanthene derivates with odorless sodium sulfinates.Various 9H-xanthenes,thioxanthenes,and 9,10-dihydroacridines are efficiently transformed into the desired benzylic sulfonyl products via a radical/radical cross-coupling process,proceeding with the merits of broad substrate scope,operational simplicity,good functional group compatibility,and mild reaction conditions.