Euglycemia despite a sodium glucose co-transporter 2 inhibitor overdose

• 作者: Muhammad Akbar Baig Joshua Nogar
• 来源期刊: 世界急诊医学杂志（英文版）
• 年，卷（期）: 2022,（2）
• 所属期刊栏目: Case Letters
• 页码范围: 147-148
• 页数: 2页
• 语种: 中文
• DOI: 10.5847/wjem.j.1920-8642.2022.050

摘要

Dear editor, Sodium glucose co-transporter 2 inhibitors (SGLT2I) reduce the majority of reabsorption of glucose in the proximal tubules, which reduces blood glucose levels by allowing excretion of excess glucose in the urine.[1] By inhibiting glucose reabsorption, they increase the osmotic pressure of urine resulting in diuresis which can cause a reduction of blood pressure.[2] Fortunately, as these drugs are not directly implicated in altering glucose metabolism or causing insulin secretion, SGLT2I monotherapy does not result in severe hypoglycemia.