药学学报(英文版)2019年第5期出版文献-钛学术文献服务平台

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688

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药学学报(英文版)

投稿

Acta Pharmaceutica Sinica B

CSTPCD

影响因子 1.2053

ISSN：

2211-3835

CN：

10-1171/R

出版周期：

双月刊

邮编：

100050

地址：

北京市先农坛街1号

出版文献量（篇）

688

总下载数（次）

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1. Targeting the untargetable KRAS in cancer therapy

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 871-879

摘要： RAS is one of the most well-known proto-oncogenes.Its gain-of-function mutations occur in appro...
2. Structural simplification: an efficient strategy in lead optimization

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 880-901

摘要： The trend toward designing large hydrophobic molecules for lead optimization is often associate...
3. Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 902-922

摘要： In last few years,therapeutic peptides/proteins are rapidly growing in drag market considering ...
4. Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven protumorigenic senescent secretion

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 923-936

摘要： It is critical to regulate the senescence-associated secretory phenotype (SASP) due to its effe...
5. Synergistic antitumor activity of artesunate and HDAC inhibitors through elevating heme synthesis via synergistic upregulation of ALAS1 expression

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 937-951

摘要： Artemisinin and its derivatives (ARTs) were reported to display heme-dependent antitumor activi...
6. Direct interaction of DNMT inhibitors to PrPC suppresses pathogenic process of prion

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 952-959

摘要： The conversion of the normal cellular prion protein (PrPC) to the misfolded pathogenic scrapie ...
7. Improvement in affinity and thermostability of a fully human antibody against interleukin-17A by yeast-display technology and CDR grafting

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 960-972

摘要： Monoclonal antibodies (mAbs) are widely used in many fields due to their high specificity and a...
8. Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 973-985

摘要： The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage polar...
9. Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 986-996

摘要： Imipenem is a carbapenem antibiotic.However,Imipenem could not be marketed owing to its instabi...
10. Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 997-1007

摘要： We have previously shown that high expression of the nucleic acid binding factor YB-1 is strong...
11. Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1008-1020

摘要： Renal cell carcinoma (RCC) is one of the most common malignant tumors affecting the urogenital ...
12. MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1021-1034

摘要： Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment.Although...
13. High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1035-1049

摘要： Managing the dysregulated host response to infection remains a major challenge in sepsis care.C...
14. Injectable peptide hydrogel as intraperitoneal triptolide depot for the treatment of orthotopic hepatocellular carcinoma

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1050-1060

摘要： Chemotherapy is among the limited choices approved for the treatment of hepatocellular carcinom...
15. Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1061-1077

摘要： Recently,considerable attention in the field of cancer therapy has been focused on the mammalia...
16. The dimerization of ⊿9-tetrahydrocannabinolic acid A (THCA-A)

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1078-1083

摘要： The renewed interest in dimeric salicylates as broad-spectrum anti-inflammatory and antidiabeti...
17. New era of drug innovation in China

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 1084-1085

摘要： In 2018, the China National Medical Products Administration (NMPA) approved new drug applicatio...
18. Information for Authors

作者：

刊名：药学学报(英文版)

发表期刊： 2019年5期

页码: 后插1-后插4

摘要：

药学学报(英文版)基本信息

刊名	药学学报(英文版)	主编
曾用名
主办单位		主管单位
出版周期	双月刊	语种	eng
ISSN	2211-3835	CN	10-1171/R
邮编	100050	电子邮箱	yxxb@imm.ac.cn
电话	010-63026192	网址
地址	北京市先农坛街1号

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