【正】 Using the molecular orbital theory including α transfer mechanism, calculations arepresented of the sub-barrier fusion cross sections for the important astrophysically interestingreactions <sup>16</sup>O+<sup>16</sup>O. The resulting cross sections and S-factors are much larger than previousoptical model results at E<sub>c.m.</sub>=5 MeV and below, although they are in agreement with eachother in a higher energy region. The corresponding reaction rate at temperature 4×10<sup>5</sup> K ex-ceeds the previous predictions by about 6 orders. This probably means that, in stellar interior,the occurrence of <sup>16</sup>O+<sup>16</sup>O fusion may be easier than previously thought.