STRUCTURE STUDIES OF PLATINOTHIONEINS BY USING EXTENDED X—RAY ASSORPTION FINE STRUCTURE SPECTROSCOPY

• 作者: BenggangXiang TiandouHu
• 来源期刊: 同步辐射装置用户科技论文集
• 学科: 化学
• 关键词: 金铂合金 巯基组氨酸三甲内盐 X射线吸收 精细结构
• 年，卷（期）: 1999,（1）
• 页码范围: 44-54
• 页数: 11页
• 分类号: O627.8

摘要

The metal binding sites in the two Pt containing metallothioneins (Pt-MT and Pt14MT) were examined by means of Pt(II) L3-edge extended X-ray absorption rine structure(EXAFS) spectroscopy.Comparisons between the phase and amplitude functions derived from the isolated shells to those of Pt…Pt.Pt-S and Pt-N model components showed that each platinum in Pt7MT was coordinated by four sulfur atoms at a distance of 2.31±0.01 A.Analysis of the outer shell data of platinum atom in Pt7MT indicated backscattering platinum atom at approximate 4.29A.Strkingly different structural parameters had been obtained for the Pt14MT species.fitting of the first shell revealed that each platinum was coordinated by two sulfurs at the distance of 2.3-±0.02A and two nitrogens at 2.02±0.02A.The results of the work provided the detailed information concerning the local environments of the coordinated Pt(II) in these two platinothioneins.