EFFECT OF ACUPUNCTURE ON β-EP CONTENT IN THE BRAIN TISSUE OF RATS WITH ACUTE CEREBRAL INFARCTION

• 来源期刊: 世界针灸杂志(英文版)
• 学科: 医学
• 关键词: 缺氧缺血性脑损伤 多系统器官功能衰竭 脑缺血损伤 防治作用 诊断治疗 急症 实验研究 针刺研究 急性脑血管病 科学技术
• 年，卷（期）: 2001,（2）
• 页码范围: 22-25
• 页数: 4页
• 分类号: R246.6
• 语种: 中文

摘要

Objective: To study the mechanisms of acupuncture in treatment of acute cerebral infarction. Methods: 90 SD rats were randomly divided into normal control group (n=10), model group (n=40) and electroacupuncture (EA) group (n=40). Shuigou (GV 26), bilateral Neiguan (PC 6) and Zusanli (ST 36) were stimulated with EA for 20 min. Acute cerebral infarction (ACI) was produced by blocking blood flow of the cerebral middle artery. Changes of β EP content in the brain tissue after ACI and EA were detected by radioimmunoassay (RIA). Results: 24 hour after ACI, plasma β EP content increased significantly to 1120.41±33.79 ng/L from 401.72±266.47 ng/L before ACL. While after acupuncutre, the increased β EP content lowered evidently in comparison with that of model group but was close to that of normal group. Conclusion: Acupuncture may adjust the neuroendocrine disturbance in rats with acute cerebral infarction to minimize the injury of the brain tissue.