ESTABLISHMENT OF IN VITRO CELLULAR MODEL PREDICTING HISTOCOMPATIBITY IN ALLOGRAFT

• 来源期刊: 同济医科大学学报(外文版)
• 学科: 医学
• 关键词: 湖北 病毒 实验技术 现代免疫学 转化 皮片移植 科技出版社 淋巴细胞 不同方法 医科大学学报
• 年，卷（期）: 2001,（4）
• 页码范围: 277-279
• 页数: 3页
• 分类号: R392
• 语种: 中文

摘要

A novel in vitro cellular model prodicting recipient donor histocompatibility in allograft was developed to select the donor validly. Fifteen couples of blood samples of donor and recipient in human BMT were examined using the model, and skin allograft in mice was performed to test the model. The results showed that the less the differences of histocompatibility evaluated by the model were, the later GVHR in human BMT occurred and the longer the survival time of skin allografts in mice. It was suggested that the model could be used to predict correctly histocompatibility between donor and recipient.