THE CHANGES OF PERIPHERAL BLOOD T LYMPHOCYTE SUBSETS IN PATIENTS WITH PRIMARY HEPATIC CARCINOMA BOTH PRE-TACE AND POST-TACE

• 作者: Chen Chenguang(隋晨光) Chunli(李春丽) Kejun(南克俊) Li Liu Nan Sui Wei Wei(陈葳) Yamin(刘亚民) Yongchang(魏永长)
• 来源期刊: 西安交通大学学报：英文版
• 学科: 医学
• 关键词: PRIMARY HEPATIC CARCINOMA T lymphocyte SUBSET flow cytometry TRANSCATHETER arterial CHEMOEMBOLIZATION
• 年，卷（期）: 2002,（2）
• 页码范围: 174-176
• 页数: 3页
• 分类号: R735.7

摘要

Objective To observe the variations of the cellular immunological function in patients with primary hepatic carcinoma both pre-TACE (transcatheter arterial chemoembolization, TACE). Methods T lymphocyte subset CD4, CD8 and CD4/CD7 ratio in 45 patients with primary hepatic carcinoma both pre-TACE and post-TACE were measured by flow Cytometer, and compared with the result of T lymphocyte subset in 19 healthy people as normal control samples. Results The CD4 and CD4/CD8 ratio in patients with primary hepatic carcinoma were significantly lower than those in normal control (P＜0.05), while CD8 higher (P＜0.05); The CD4 and CD4/CD8 ratio in patients with primary hepatic carcinoma were much more lower after TACE than those before TACE (P＜0.05), while CD8 was higher but had no significant difference (P＞0.05). Conclusion The cellular immunological function in patients with primary hepatic carcinoma decreased and is much more lower after TACE.