蛋白质的膨胀床吸附过程穿透模型分析

• 作者: 史清洪 孙彦 陈卫东
• 来源期刊: 磁流体发电情报
• 学科: 生物学
• 关键词: 蛋白质 膨胀床 吸附过程 穿透模型 生物分离模式
• 年，卷（期）: 2004,（3）
• 页码范围: 501-504
• 页数: 4页
• 分类号: Q51

摘要

Using the fundamental adsorption equilibrium and kinetic parameters obtained from batch experiments, the mass transport and hydrodynamic behavior in the expanded bed of DEAE Spherodex M was analyzed with the breakthrough model. The results showed that the effect of particle size on breakthrough behavior was obviously greater than that of other parameters. The change of the time of 5% breakthrough, with increasing and decreasing mean particle diameter by a factor of 2, reached about 40% relative to that with the mean diameter, 88μm. Secondary effects on expanded bed adsorption were film mass transfer and pore diffusion (<10%). Axial dispersion in solid phase had almost negligible effect on the adsorption process. Therefore, the assumption of even dispersion of adsorbent within the expanded bed may result in the model discrepancy to a great extent. It is considered that the breakthrough model can be further improved by taking into account particle size distribution in the expanded bed.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	陈卫东	天津大学化工学院生物化工系	76	903	16.0	28.0
2	史清洪	天津大学化工学院生物化工系	23	117	5.0	10.0
3	孙彦	天津大学化工学院生物化工系	82	902	16.0	26.0