Partition of Chiral pharmaceutical intermediate R(-)-Mandelic Acid in Aqueous Two-Phase System of Poly(ethylene glycol)-Ammonium Sulfate

• 来源期刊: 中国新医药
• 学科: 医学
• 关键词: Partition Aqueous two-phase system R(-)-mandelic acid polyethylene glycol
• 年，卷（期）: 2004,（1）
• 所属期刊栏目: 医药研究(论著与综述)
• 页码范围: 24-25
• 页数: 2页
• 分类号: R9
• 语种: 中文

摘要

An aqueous two-phase system of poly (ethylene glycol)-ammonium sulfate was employed to separate R (-)-mandelic acid.The result showed that R (-)-mandelic acid has priority to partition in PEG-rich top phase. This indicated that aqueous two-phase is a very suitable system for separation of R(-)-mandelic acid.