Monte Carlo Simulation on Growth of Antibody-Antigen Complexes: the Role of Unequal Reactivity

• 作者: 张平 王海军
• 来源期刊: 中国物理快报(英文版)
• 学科: 化学
• 关键词: 蒙特卡罗模拟方法 反应性 复合物 抗原 抗体 生长 不等 凝胶化反应
• 年，卷（期）: 2010,（3）
• 页码范围: 328-331
• 页数: 4页
• 分类号: O631.5 V55
• 语种: 英文

摘要

Growth of Antibody-Antigen complexes in a multivalent Antibody-Antigen system is studied by the Monte Carlo simulation method. The validity of the algorithm is first demonstrated for the case of the equal reactivity, then the simulation is presented for the case of unequal reactivity. It is shown that the influence of the unequal reactivity on the critical point, size distribution and the weight-average binding degree is significant. Especially, the gelation regions for the cases of unequal reactivity are studied, which can provide some useful clues for the immunological experiments.