Anaerobic Biotransformation of Nitro-Compounds to Amines by Bovine Rumen Fluid

• 作者: Alfonso Rodríguez Cecilia Cajarville Guzmán álvarez Hugo Cerecetto Ignacio Irazoqui José Luis Repetto Mercedes González
• 来源期刊: 绿色与可持续化学(英文)
• 学科: 化学
• 关键词: BIOTRANSFORMATION NITRO-COMPOUNDS AMINES RUMEN RUMINAL Fluid BOVINE
• 年，卷（期）: 2011,（3）
• 页码范围: 47-53
• 页数: 7页
• 分类号: O6

摘要

Microorganims of the bovine rumen fluid biocatalyzed the reduction of nitro-compound substrates to yield the respective amines. This enzymatic process, using ruminal contents, has rarely been reported in associa- tion with the bioreduction of nitro groups. The biotransformation reactions catalyzed by this system were de- pendent of both the electronic characteristics and the area/volume of the nitro-substrates confirming the processes are enzymatic. The semi-preparative scale biotransformation went by in good yield showing the rumen fluid may be employed in the synthesis of amines under very mild conditions and, moreover, it may have application in the bioremediation of nitro-compounds.