Eco-friendly Synthesis of Cyclododecanone from Cyclododecatriene

• 作者: Dao-Quan Wang De-Kai Yuan Fu-Heng Chen Jian-Jun Zhang Jin-Ping Wu Qi Feng Xiao-Mei Liang
• 来源期刊: 绿色与可持续化学(英文)
• 学科: 化学
• 关键词: ECO-FRIENDLY SYNTHESIS CYCLODODECANONE Cyclododecatriene Hexadecyl Trimethyl AMMONIUM Heteropolyphosphatotungstate
• 年，卷（期）: 2011,（3）
• 页码范围: 63-69
• 页数: 7页
• 分类号: O6

摘要

An eco-friendly synthesis of cyclododecanone (CDON) from cyclododecatriene (CDT) is described. Selec- tive epoxidation of CDT with hydrogen peroxide using hexadecyl trimethyl ammonium heteropolyphospha- totungstate [(n-C16H33NMe3)3PW4O16, HAHPT] as catalyst and water as solvent followed by the hydrogena- tion on Raney nickel catalyst gave cyclododecanol (CDOL). The latter was oxidized with hydrogen peroxide using HAHPT as catalyst and a mixture of water and t-butanol as solvent to afford CDON. The total yield was 53.4% under the optimum reaction conditions.