Spectral Analysis and Crystal Structure of Spiro[2.2”] Acenaphthene-1”-One-Spiro[3.3’]-5’-(2,3-Dichlorophenyl Methylidene)-1’-Methylpiperidin-4’-One-4- (2,3-Dichlorophenyl) Octahydroindolizine

• 作者: Janakiraman Suresh Raju Ranjith Kumar Rakkappan Vishnu Priya Sathiyamoorthi Sivakumar
• 来源期刊: 晶体结构理论与应用(英文)
• 学科: 化学
• 关键词: Single Crystal Structure Conformation Hydrogen Bond NMR Spectra
• 年，卷（期）: 2012,（3）
• 页码范围: 74-78
• 页数: 5页
• 分类号: O6

摘要

The crystal structure of spiro[2.2”]acenaphthene-1”-onespiro[3.3’]-5’-(2,3-dichlorophenylmethylidene)-1’-methylpipe-ridin-4’-one-4-(2,3-dichorophenyl) octahydroindolizine was elucidated by single crystal X ray diffraction. The title compound C37H30Cl4N2O2, crystallizes in the orthorhombic system, space group P212121 with a = 8.4610(4) , b = 16.0926(6) , c= 23.8997(11) and Z = 4. The central piperidine ring adopts twisted conformation, the piperidine of octahydroindolizine ring is in chair conformation and the pyrrole ring is in slightly twisted envelope conformation. Details of the synthesis, NMR, crystal structure determination and intra- and inter- molecular interactions of the compound are given.