Epithelioid Angiosarcoma of Bone: A Neoplasm with Potential Pitfalls in Diagnosis

• 作者: Deng Li Jie Xu Liang-Ping Li Ruo-Fan Ma Wen-Wu Dong Yan Chen Yue Ding Zhi-Qing Cai
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: ANGIOSARCOMA BONE NEOPLASMS Vascular Tissue NEOPLASMS ANEURYSMAL BONE Cysts PITFALL
• 年，卷（期）: 2012,（3）
• 页码范围: 80-84
• 页数: 5页
• 分类号: R73

摘要

Angiosarcoma of bone is an exceedingly rare primary bone malignancy that can present as an aggressive osteolytic lesion. This subset can radiologically mimic non-vascular neoplasms and impose serious challenges in reaching the correct diagnosis. Meanwhile histological diagnosis can be extremely challenging too, as the pathological features often resemble that of aneurysmal bone cysts. We present an unusual case of a 22-year-old woman who presented with a rapidly growing humeral tumor of 8 months’ duration. The case of intraosseous angiosarcoma presented as a diagnostic dilemma and the relevant radiological and pathologic findings were discussed. We describe the clinical, radiological and pathological features of this unique case, and review the literature concerning Angiosarcoma of bone. Our case highlights the diagnostic difficulties for such very rare tumours and clinico-pathological correlation is of paramount importance to differential diagnosis.