在周期性的 glucagonoma 的骨头损害: 一份案例报告和文学的评论

• 作者: Cristian Ghetie Daniel Cornfeld Vassilios S Ramfidis Kostas N Syrigos Muhammad W Saif
• 来源期刊: 世界胃肠肿瘤学杂志：英文版（电子版）
• 学科: 医学
• 关键词: GLUCAGONOMA BONE METASTASES BLASTIC LESION Octreoscan
• 年，卷（期）: 2012,（6）
• 页码范围: 152-155
• 页数: 4页
• 分类号: R738

摘要

Glucagonomas are rare neuroendocrine tumors that arise from cells of the pancreatic islets. Most of them are malignant and usually present as metastatic disease. Sites most commonly involved in metastases are the liver and regional lymph nodes. Bone metastases are rare events and only a few cases have been reported in the literature. We present the case of a 53-year-old male with a medical history of recurrent non-functioning glucagonoma. He presented 17 years after the initial diagnosis with new blastic bone lesions involving the T1 vertebra and the sacrum. Diagnostic steps and medical management in metastatic glucagonoma are also reviewed.