Sensitive Voltammetric Determination of Mitoxantrone by Using CS-Dispersed Graphene Modified Glassy Carbon Electrodes

• 作者: Bin Hong Qiong Cheng
• 来源期刊: 化学工程与科学期刊(英文)
• 学科: 化学
• 关键词: MITOXANTRONE CS-Dispersed GRAPHENE Modified ELECTRODE VOLTAMMETRY
• 年，卷（期）: 2012,（4）
• 页码范围: 453-460
• 页数: 8页
• 分类号: O6

摘要

A novel CS-dispersed graphene modified glassy carbon electrode was fabricated. Study electrochemical characteristics of mitoxantrone in the CS-dispersed graphene modified electrode by cyclic voltammetry and other methods, by selecting and optimizing the various parameters to create a new electrochemical method for the determination of mitoxantrone. The linear range of the oxidation peak current is from 6×10–10 to 1 ×10–6 mol/l in this method, after 2.5 mins open-circuit accumulation, the limit of detection is 2×10–10 mol/l. After 10 parallel determinations, the relative standard deviation was 3.7% that the concentration of mitoxantrone was 1×10–8 mol/l. The modified electrode has been successfully applied for the assay of mitoxantrone in human urine samples.