为深大脑刺激的成像: 在 7 泰斯拉的带 incerta

• 作者: Armin M Nagel Christoph Groden Hans U Kerl Ingo S Nlte Lars Gerigk Mansour AlZghloul Marc A Brockmann Sonia Huck Thomas Hauser
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Deep brain STIMULATION Essential TREMOR Magnetic resonance imaging Parkinson’s disease Zona incerta 7 TESLA
• 年，卷（期）: 2013,（1）
• 页码范围: 5-16
• 页数: 12页
• 分类号: R445.2

摘要

AIM:To evaluate different promising magnetic resonance imaging(MRI) methods at 7.0 Tesla(T) for the pre-stereotactic visualization of the zona incerta(ZI).METHODS:Two neuroradiologists qualitatively and quantitatively examined T2-turbo spin-echo(T2-TSE),T1-weighted gradient-echo,as well as FLASH2D-T2Star and susceptibility-weighted imaging(SWI) for the visualization of the ZI at 7.0 T MRI.Delineation and image quality for the ZI were independently examined using a 6-scale grading system.Inter-rater reliability using Cohen’s kappa coefficient(κ) were assessed.Contrast-tonoise ratios(CNR),and signal-to-noise ratios(SNR) for the ZI were calculated for all sequences.Differences in delineation,SNR,and CNR between the sequences were statistically assessed using a paired t-test.For the anatomic validation the coronal FLASH2D-T2Star images were co-registered with a stereotactic atlas(Schaltenbrand-Wahren).RESULTS:The rostral part of the ZI(rZI) could easily be identified and was best and reliably visualized in the coronal FLASH2D-T2Star images.The caudal part was not definable in any of the sequences.No major artifacts in the rZI were observed in any of the scans.FLASH2D-T2Star and SWI imaging offered significant higher CNR values for the rZI compared to T2-TSE images(P 】 0.05).The co-registration of the coronal FLASH2D-T2Star images with the stereotactic atlas schema(Schaltenbrand-Wahren) confirmed the correct localization of the ZI in all cases.CONCLUSION:FLASH2D-T2Star imaging(particularly coronal view) provides the reliable and currently optimal visualization of the rZI at 7.0 T.These results can facilitate a better and more precise targeting of the caudal part of the ZI than ever before.