Necrotizing Scleritis Associated with 5-Fluorouracil and Sub-Tenon’s Block in Patient with Previous Trabeculectomy: A Case Report

• 作者: Dan Nguyen Jeremy O’Connor Tu Tran Tuan A. Tran Xavier Fagan
• 来源期刊: 眼科学期刊(英文)
• 学科: 医学
• 关键词: NECROTIZING SCLERITIS 5-FLUOROURACIL Sub-Tenon’s Block Glaucoma
• 年，卷（期）: 2013,（3）
• 页码范围: 73-75
• 页数: 3页
• 分类号: R73

摘要

Necrotizing scleritis is the most severe form of scleritis with a significant threat to vision and globe integrity. It can be infectious, surgically induced necrotizing scleritis (SINS) or systemic autoimmune associated. We report a case of necrotizing scleritis associated with 5-fluorouracil (5-FU) at the site of sub tenon’s block in a patient with previous trabeculectomy. To our knowledge, this is the first reported case of necrotizing scleritis associated with 5-FU. This may implicate alternative approaches to local anaesthetic techniques when using adjunctive 5-FU.