Modelling One-Pot Method for Synthesis of 2,3-Dihydro-1<i>H</i>-pyrrolo[2,1-<i>c</i>][1,4]benzothiazine 5,5-Dioxides and Their Homologues

• 作者: Anna B. Bondarenko Oleg V. Zaremba Oleksandr G. Drushlyak Oleksandr Yu Grevtsov Sergiy M. Kovalenko Valentyn P. Chernykh
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: SULFONES Lactims Cyclization Heterocycles NUCLEOPHILIC Aromatic Substitution
• 年，卷（期）: yjhxgjqkyw,（2）
• 页码范围: 125-135
• 页数: 11页
• 分类号: O6

摘要

A facile method for synthesis of 2,3-dihydro-1H-pyrrolo[2,1-c][1,4]benzothiazines by interaction of methylenactive (2-fluorophenyl)sulfones with homologues of either 5-methoxy-3,4-dihydro-2H-pyrrole or 5-(methylthio)-3,4-dihydro- 2H-pyrrole has been developed.