New Greener Alternative for Biocondensation of Aldehydes and Indoles Using Lemon Juice: Formation of Bis-, Tris-, and Tetraindoles

• 作者: Rammohan Pal
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: Citrus limon JUICE Biocondensation ALDEHYDES INDOLES Aqueous Ethanol Sonication Bis- Tris- Tetraindoles
• 年，卷（期）: yjhxgjqkyw,（2）
• 页码范围: 136-142
• 页数: 7页
• 分类号: O6

摘要

This work presents a new greener alternative for biocondensation of aldehydes and indoles for the synthesis of bis- and tris(indolyl)methanes catalyzed by lemon juice (Citrus limon) in good yields under ultrasound irradiation in aqueous ethanol. Various substituted aldehydes with indoles under this reaction condition are elucidated. Also, tetraindolyl compounds were prepared using terephthaldialdehyde by following the same protocol. This method is an environmentally benign, efficient reaction, which requires shorter reaction time and simple experimental and work-up procedures.