Recent Advances of Modern Protocol for C-C Bonds—The Suzuki Cross-Coupling

• 作者: Agnieszka ?wist Dorota Zaj?c Jadwiga So?oducho Joanna Cabaj Kamila Olech
• 来源期刊: 化学工程与科学期刊(英文)
• 学科: 化学
• 关键词: C-C BOND Formation COUPLING Reactions PALLADIUM Catalysts SUZUKI COUPLING HETEROCYCLIC COPOLYMERS
• 年，卷（期）: 2013,（3）
• 页码范围: 19-32
• 页数: 14页
• 分类号: O6

摘要

Over the past 20 years, small molecule solid phase synthesis has become a powerful tool in the discovery of novel molecular materials. In the development of organic chemistry, the carbon-carbon bond formation has always been one of the most useful and fundamental reaction. The current review summarizes recent developments in metal-catalyzed coupling reactions. The following method is discussed in detail—the cross-coupling of aryl halides with aryl boronic acids (the Suzuki coupling), and the others C-C bond formation reactions as the palladium-catalyzed reaction between an aryl and (or) alkyl halide and a vinyl functionality (the Heck reaction);and the palladium-catalyzed cross-coupling reaction of organostannyl reagents with a variety of organic electrophiles (the Stille reaction)—are mentioned.