Efficacy of deferasirox for the treatment of iron overload in a child affected by Juvenile Hemochromatosis

• 作者: Alberto Piperno Alessandro Cattoni Cristina Arosio Nicoletta Masera Raffaella Mariani Valentina Decimi Valeria D’Apolito
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: Juvenile HEMOCHROMATOSIS DEFERASIROX IRON CHELATION CHILD IRON OVERLOAD
• 年，卷（期）: 2013,（2）
• 页码范围: 126-128
• 页数: 3页
• 分类号: R5

摘要

We report the case of a 7 years old girl with Juvenile Hemochromatosis, due to homozygous mutation of HJV, which had increased serum iron indices and liver iron overload in the absence of any clinical sign of disease. Oral iron chelation with low dose deferasirox showed good efficacy and no side effects. The oral iron chelator deferasirox could be a valid option for removing excess iron in early Juvenile Hemochromatosis.