Recurrent ameloblastoma of the mandible: Surgical seeding or metastasis of malignant ameloblastoma?

• 作者: Andreas Thor Christina Klee Jan-M. Hirsch Sven Lindskog
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: AMELOBLASTOMA SURGICAL SEEDING METASTASIS
• 年，卷（期）: 2013,（2）
• 页码范围: 154-158
• 页数: 5页
• 分类号: R73

摘要

The controversy of surgical seeding or metastasis of a recurrent ameloblastoma is discussed in this paper, where we present a case with a history of 28 years since primary diagnosis including several tumor removals and reconstructive events. 23 years after primary diagnosis, we removed a metastasis from the neck with similar histological features as the primary tumor and the following recurrences of the mandible. We argue that the removed tumor in the neck most possibly has its origin in surgical seeding of cells during earlier resection and reconstruction and not by common ways of metastasis. The seeding of tumor cells during tumor surgery and metastasis rate of malignant ameloblastoma is discussed and the literature in this area is reviewed in the paper.