Successful Treatment of Spine Fracture for Diffuse Idiopathic Skeletal Hyperostosis with Teriparatide—A Report of Two Cases

• 作者: Akihito Wada Daisuke Suzuki Hiroshi Takahashi Katsunori Fukutake Kazumasa Nakamura Keiji Hasegawa Masayuki Sekiguchi Ryo Takamatsu Shintaro Tsuge Wataru Shishikura Yasuaki Iida Yasuhiro Inoue Yuichiro Yokoyama
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS TERIPARATIDE SPINE Fracture
• 年，卷（期）: 2013,（6）
• 页码范围: 278-282
• 页数: 5页
• 分类号: R6

摘要

We experienced 2 cases of spinal fracture in patients aged 80 years or older with diffuse idiopathic skeletal hyperostosis (DISH). Since they decided not to undergo surgical treatment, we provided conservative treatment with teriparatide. There has been no previous study on teriparatide for spine fracture in DISH. This is the first report of the successful use of teriparatide to treat spine fracture in DISH without surgical intervention. Our patients were treated with teriparatide for 8-9 months after diagnosis of the fracture. Union was obtained in two cases and no adverse events were observed during treatment. Our report showed that teriparatide could be an alternative to conventional intervention in spinal fracture of DISH.