In the article the features of the formation and metallogeny of the geological structures of Great Altai (Rudny Altai, Kalba-Narym, Western Kalba and Jarma-Saur) which are included into the system of the Central Asian mobile belt are considered. The characteristic of the main types of rare metal minefields of the Kalba-Narymsky belt genetically connected with the Perm granitoid magmatism of the post-conflict orogenny stage of activization is given. The rhythmical and pulsation model of pegmatitovy ore formation in the conditions of the half-closed magmatic system, reflecting the phasic development of mineral complexes from graphic and oligoclase-microcline (barren) to microcline-albite and albite-spodumene ore (Ta, Nb, Be, Li, Sn, etc.) is developed. On the basis of the revealed criteria of ore formation recommendations about the direction of the further researches are made.