Higgs boson production in association with heavy quarks is one of the most important discovery channels for Higgs particles in the Standard Model and its super-symmetric extension at the LHC pp collider. We review the status of the Higgs boson studies, with particular emphasis on the case bbh and tth production. We present results for the total cross section at Large Hadron Collider (LHC) in both single and double parton scattering mechanism.