New options for uveitis treatment

• 作者: Jing-Ming Shi Song-Bai Jia Wei Zhang Yu He
• 来源期刊: 国际眼科杂志：英文版
• 学科: 医学
• 关键词: UVEITIS intravitrealimplants biologicagents GENE THERAPY RNA INTERFERENCE
• 年，卷（期）: 2013,（5）
• 页码范围: 701-706
• 页数: 6页
• 分类号: R77

摘要

· Uveitis is one of the most important causes of blindness worldwide. Its etiology and pathogenesis are complicated and have not been well understood. The treatment for uveitis is predominantly based on steroids and immunosuppressants. However, systemic side effects limit their clinical application. With the advancement of molecular biology, some intravitreal implants and biologic agents have been used for the treatment of uveitis. Additionally, novel techniques such as gene therapy and RNA interference are being studied for using as uveitis therapy. This paper reviews recent advances in uveitis treatment. ·