Hypertension Unusual Cause

• 作者: Alfonso López Ruiz Alicia Hernández Torres Ana Belén Hernández Cascales Juan Mayor Barrancos María ángeles Ibá?ez Gil María Dolores Hellín Gil Pedro Pujante Alarcón
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: LICORICE Glycyrrhizic ACID Glycyrrhizinic ACID Induced HYPERTENSION HYPOKALEMIA
• 年，卷（期）: 2014,（1）
• 页码范围: 1-3
• 页数: 3页
• 分类号: R5

摘要

We expose a case of a woman with hypertension and hypokalemia. The differential diagnosis should include primary hyperaldosteronism, diuretics or lazantes intake, secondary hyperaldosteronism. In this patient, additional tests performed show no cause of hormonal disruption and the whole picture is due to a high intake of licorice. Glycyrrhetinic acid, the active component of licorice, inhibits renal IIbeta-hydroxisteroid dehydrogenase. This allows cortisol to stimulate mineralocorticoid receptors. Licorice ingestion should be considered in the differential diagnosis of hypertension with hypokalemia.