Acute renal failure secondary to lupus nephritis confirmed by renal biopsy with an unusually normal immunological profile

• 作者: Andrew Ofosu Navdeep Grewal Richard Williams Zhigang Liu
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: LUPUS NEPHRITIS Anti-Ds DNA C3 C4 IMMUNOLOGICAL PROFILE
• 年，卷（期）: 2014,（1）
• 页码范围: 6-9
• 页数: 4页
• 分类号: R5

摘要

The gold standard to diagnose the lupus nephritis is the renal biopsy. It provides information not only for diagnosis but also for the treatment plan and the prognosis. Laboratory studies, including the immunological profile, play an essential role in diagnosing and evaluating the lupus nephritis activity. The patient is unlikely to have the active lupus nephritis with the combination of anti-ds DNA, anti-C1q, C3 and C4 being within normal limits. In this case report, we present a patient with moderately active diffuse proliferative lupus glomerulonephritis (Class IV) confirmed by the renal biopsy, while her immunological profile is unusually normal.