Role of Apoptosis in Microbial Infection

• 作者: Ahmed Q. Alotaibi Anwar M. Alanazi Faisal M. Alanazi Faris Q. Alenzi Gdhi M. Almotiri Khalaf A. Alanazi Mohammed J. Alenzi Mohammed S. Alenazi Shamweel Y. Ahmad
• 来源期刊: 细胞凋亡(英文)
• 学科: 医学
• 关键词: APOPTOSIS MICROBIAL PATHOGENS INFECTION THERAPY
• 年，卷（期）: 2014,（2）
• 页码范围: 32-38
• 页数: 7页
• 分类号: R73

摘要

Apoptosis plays a central role in the pathogenesis of a number of human diseases. Because apoptosis represents a fundamental process in the response to such infections, it may represent a therapeutic target for their treatment. There is thus likely to be future clinical relevance in harnessing our growing knowledge both of apoptotic mechanisms, and their regulation, in the search to achieve modalities for therapeutic benefit. This brief review aims to summarize what we currently know about the role of apoptosis in response to a range of microbial infections (including bacterial and viral).