<i>In-Vitro</i>Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth

• 作者: James L. Cox Pandurangan Ramaraj
• 来源期刊: 细胞生物学(英文)
• 学科: 医学
• 关键词: Sex STEROIDS B16 Mouse MELANOMA MTT Growth Assay
• 年，卷（期）: 2014,（2）
• 页码范围: 60-71
• 页数: 12页
• 分类号: R73

摘要

A battery of sex steroids were used to check their effect on mouse melanoma (B16F10) cell growth in-vitro. Progesterone and its synthetic receptor antagonist RU-486 showed maximum inhibition on in-vitro melanoma cell growth [1]. Further research work showed that the inhibition by progesterone was not a toxic, spurious or non-specific effect on mouse melanoma cell growth and the inhibition by progesterone was not mediated through progesterone receptor.